oxLDL induces endothelial cell proliferation via Rho/ROCK/Akt/p27(kip1) signaling: opposite effects of oxLDL and cholesterol loading

Oxidized modifications of LDL (oxLDL) play a key role in the development of endothelial dysfunction and atherosclerosis. However, the underlying mechanisms of oxLDL-mediated cellular behavior are not completely understood. Here, we compared the effects of two major types of oxLDL, copper-oxidized LD...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Zhang, Chongxu, Adamos, Crystal, Oh, Myung-Jin, Baruah, Jugajyoti, Ayee, Manuela A. A., Mehta, Dolly, Wary, Kishore K., Levitan, Irena
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625097/
https://ncbi.nlm.nih.gov/pubmed/28701359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00249.2016
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