Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis

Nucleic acids, which constitute the genetic material of all organisms, are continuously exposed to endogenous and exogenous damaging agents, representing a significant challenge to genome stability and genome integrity over the life of a cell or organism. Unrepaired DNA lesions, such as single- and...

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Pubblicato in:Sci Rep
Autori principali: Fakouri, Nima Borhan, Durhuus, Jon Ambæk, Regnell, Christine Elisabeth, Angleys, Maria, Desler, Claus, Hasan-Olive, Md Mahdi, Martín-Pardillos, Ana, Tsaalbi-Shtylik, Anastasia, Thomsen, Kirsten, Lauritzen, Martin, Bohr, Vilhelm A., de Wind, Niels, Bergersen, Linda Hildegard, Rasmussen, Lene Juel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624938/
https://ncbi.nlm.nih.gov/pubmed/28970491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12662-3
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