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Preformulation and Vaginal Film Formulation Development of Microbicide Drug Candidate CSIC for HIV prevention

PURPOSE: 5-chloro-3-[phenylsulfonyl] indole-2-carboxamide (CSIC) is a highly potent non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 which has been shown to have a more desirable resistance profile than other NNRTIs in development as HIV prevention strategies. This work involves gener...

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Dettagli Bibliografici
Pubblicato in:J Pharm Innov
Autori principali: Gong, Tiantian, Zhang, Wei, Parniak, Michael A., Graebing, Phillip W., Moncla, Bernard, Gupta, Phalguni, Empey, Kerry M., Rohan, Lisa C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624728/
https://ncbi.nlm.nih.gov/pubmed/28983328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12247-017-9274-0
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