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Mapping the Binding Interface of VEGF and a Monoclonal Antibody Fab-1 Fragment with Fast Photochemical Oxidation of Proteins (FPOP) and Mass Spectrometry

We previously analyzed the Fab-1:VEGF (vascular endothelial growth factor) system described in this work, with both native top-down mass spectrometry and bottom-up mass spectrometry (carboxyl-group or GEE footprinting) techniques. This work continues bottom-up mass spectrometry analysis using a Fast...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Zhang, Ying, Wecksler, Aaron, Molina, Patricia, Deperalta, Galahad, Gross, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624547/
https://ncbi.nlm.nih.gov/pubmed/28255747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-017-1601-7
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