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Fast Photochemical Oxidation of Proteins (FPOP) Maps the Epitope of EGFR Binding to Adnectin

Epitope mapping is an important tool for the development of monoclonal antibodies, mAbs, as therapeutic drugs. Recently, a class of therapeutic mAb alternatives, adnectins, has been developed as targeted biologics. They are derived from the tenth type III domain of human fibronectin ((10)Fn3). A com...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Yan, Yuetian, Chen, Guodong, Wei, Hui, Huang, Richard Y.-C., Mo, Jingjie, Rempel, Don L., Tymiak, Adrienne A., Gross, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224620/
https://ncbi.nlm.nih.gov/pubmed/25267085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-014-0993-x
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