Pathogenic role of glycan-specific IgG antibodies in IgA nephropathy

BACKGROUND: Accumulating evidences proved the important roles of circulating IgA1-containing immune complexes (cIgA1) in IgA nephropathy (IgAN). Galactose-deficient IgA1 (Gd-IgA1) and glycan-specific IgG antibody have been identified as major components in cIgA1. Before, Gd-IgA1 was reported as a vi...

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Bibliographic Details
Published in:BMC Nephrol
Main Authors: Zhao, Yan-feng, Zhu, Li, Liu, Li-jun, Shi, Su-fang, Lv, Ji-cheng, Zhang, Hong
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623975/
https://ncbi.nlm.nih.gov/pubmed/28969604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-017-0722-3
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