PRAS40 promotes NF-κB transcriptional activity through association with p65

PRAS40 has been shown to have a crucial role in the repression of mammalian target of rapamycin (mTOR). Nonetheless, PRAS40 appears to have an oncogenic function in cancer cells. Whether PRAS40 mediates signaling independent of mTOR inhibition in cancer cells remains elusive. Here PRAS40 overexpress...

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Bibliografiska uppgifter
I publikationen:Oncogenesis
Huvudupphovsmän: Zhu, G, Qi, Q, Havel, J J, Li, Z, Du, Y, Zhang, X, Fu, H
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623906/
https://ncbi.nlm.nih.gov/pubmed/28945219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.80
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