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PRAS40 promotes NF-κB transcriptional activity through association with p65

PRAS40 has been shown to have a crucial role in the repression of mammalian target of rapamycin (mTOR). Nonetheless, PRAS40 appears to have an oncogenic function in cancer cells. Whether PRAS40 mediates signaling independent of mTOR inhibition in cancer cells remains elusive. Here PRAS40 overexpress...

詳細記述

保存先:
書誌詳細
出版年:Oncogenesis
主要な著者: Zhu, G, Qi, Q, Havel, J J, Li, Z, Du, Y, Zhang, X, Fu, H
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623906/
https://ncbi.nlm.nih.gov/pubmed/28945219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.80
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