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PRAS40 promotes NF-κB transcriptional activity through association with p65
PRAS40 has been shown to have a crucial role in the repression of mammalian target of rapamycin (mTOR). Nonetheless, PRAS40 appears to have an oncogenic function in cancer cells. Whether PRAS40 mediates signaling independent of mTOR inhibition in cancer cells remains elusive. Here PRAS40 overexpress...
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| Pubblicato in: | Oncogenesis |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623906/ https://ncbi.nlm.nih.gov/pubmed/28945219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.80 |
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