Lack of interleukin‐6 in the tumor microenvironment augments type‐1 immunity and increases the efficacy of cancer immunotherapy

Conquering immunosuppression in tumor microenvironments is crucial for effective cancer immunotherapy. It is well known that interleukin (IL)‐6, a pleiotropic cytokine, is produced in the tumor‐bearing state. In the present study, we investigated the precise effects of IL‐6 on antitumor immunity and...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ohno, Yosuke, Toyoshima, Yujiro, Yurino, Hideaki, Monma, Norikazu, Xiang, Huihui, Sumida, Kentaro, Kaneumi, Shun, Terada, Satoshi, Hashimoto, Shinichi, Ikeo, Kazuho, Homma, Shigenori, Kawamura, Hideki, Takahashi, Norihiko, Taketomi, Akinobu, Kitamura, Hidemitsu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623732/
https://ncbi.nlm.nih.gov/pubmed/28746799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13330
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