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Interleukin‐6/STAT3 signaling as a promising target to improve the efficacy of cancer immunotherapy

Overcoming the immunosuppressive state in tumor microenvironments is a critical issue for improving the efficacy of cancer immunotherapy. Interleukin (IL)‐6, a pleiotropic cytokine, is highly produced in the tumor‐bearing host. Previous studies have indicated that IL‐6 suppresses the antigen present...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Kitamura, Hidemitsu, Ohno, Yosuke, Toyoshima, Yujiro, Ohtake, Junya, Homma, Shigenori, Kawamura, Hideki, Takahashi, Norihiko, Taketomi, Akinobu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623748/
https://ncbi.nlm.nih.gov/pubmed/28749573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13332
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