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Methylmercury augments Nrf2 activity by downregulation of the Src family kinase Fyn

Methylmercury (MeHg) is a potent developmental neurotoxicant that induces an oxidative stress response in the brain. It has been demonstrated that MeHg exposure increases nuclear factor erythroid 2-related factor 2 (Nrf2) activity. Nrf2 is a transcription factor that translocates to the nucleus in r...

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Detalhes bibliográficos
Publicado no:Neurotoxicology
Main Authors: Culbreth, Megan, Zhang, Ziyan, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623621/
https://ncbi.nlm.nih.gov/pubmed/28736149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2017.07.028
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