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Integrated magnetic tweezers and single-molecule FRET for investigating the mechanical properties of nucleic acid

Many enzymes promote structural changes in their nucleic acid substrates via application of piconewton forces over nanometer length scales. Magnetic tweezers (MT) is a single molecule force spectroscopy method widely used for studying the energetics of such mechanical processes. MT permits stable ap...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: Long, Xi, Parks, Joseph W., Stone, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623588/
https://ncbi.nlm.nih.gov/pubmed/27320203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.06.009
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