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Integrated magnetic tweezers and single-molecule FRET for investigating the mechanical properties of nucleic acid
Many enzymes promote structural changes in their nucleic acid substrates via application of piconewton forces over nanometer length scales. Magnetic tweezers (MT) is a single molecule force spectroscopy method widely used for studying the energetics of such mechanical processes. MT permits stable ap...
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Publicado no: | Methods |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623588/ https://ncbi.nlm.nih.gov/pubmed/27320203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.06.009 |
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