Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy

Single-molecule techniques facilitate analysis of mechanical transitions within nucleic acids and proteins. Here, we describe an integrated fluorescence and magnetic tweezers instrument that permits detection of nanometer-scale DNA structural rearrangements together with the application of a wide ra...

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Detaylı Bibliyografya
Asıl Yazarlar: Long, Xi, Parks, Joseph W., Bagshaw, Clive R., Stone, Michael D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
Konular:
Structural Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575832/
https://ncbi.nlm.nih.gov/pubmed/23303789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1341
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