COBI (COntinuous hyperosmolar therapy for traumatic Brain-Injured patients) trial protocol: a multicentre randomised open-label trial with blinded adjudication of primary outcome

INTRODUCTION: Traumatic brain injury (TBI) is a major cause of death and severe prolonged disability. Intracranial hypertension (ICH) is a critical risk factor of bad outcomes after TBI. Continuous infusion of hyperosmolar therapy has been proposed for the prevention and the treatment of ICH. Whethe...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: Roquilly, Antoine, Lasocki, Sigismond, Moyer, Jean Denis, Huet, Olivier, Perrigault, Pierre François, Dahyot-fizelier, Claire, Seguin, Philippe, Sharshar, Tarek, Geeraerts, Thomas, Remerand, Francis, Feuillet, Fanny, Asehnoune, Karim
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2017
Soggetti:
Intensive Care
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623466/
https://ncbi.nlm.nih.gov/pubmed/28947465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-018035
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