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A population genetics perspective on the determinants of intra-tumor heterogeneity

Cancer results from the acquisition of somatic alterations in a microevolutionary process that typically occurs over many years, much of which is occult. Understanding the evolutionary dynamics that are operative at different stages of progression in individual tumors might inform the earlier detect...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Hu, Zheng, Sun, Ruping, Curtis, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623098/
https://ncbi.nlm.nih.gov/pubmed/28274726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2017.03.001
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