Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation

Aims and Hypothesis: This study aims to investigate the mechanism involved in intracellular regulation of EGFR degradation induced by EGF. Methods: Phosphorylation of proteins related to EGFR signaling was examined by western blot analysis. Activation, connection between Rab35 and folliculin (FLCN)...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zheng, Jianchao, Duan, Biao, Sun, Shixiu, Cui, Jie, Du, Jun, Zhang, Yujie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622982/
https://ncbi.nlm.nih.gov/pubmed/29018350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00688
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