Developmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System

Maternal obesity predisposes offspring to metabolic dysfunction and Non-Alcoholic Fatty Liver Disease (NAFLD). Melanocortin-4 receptor (Mc4r)-deficient mouse models exhibit obesity during adulthood. Here, we aim to determine the influence of the Mc4r gene on the liver of mice subjected to perinatal...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Cordero, Paul, Li, Jiawei, Nguyen, Vi, Pombo, Joaquim, Maicas, Nuria, Novelli, Marco, Taylor, Paul D., Samuelsson, Anne-Maj, Vinciguerra, Manlio, Oben, Jude A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622801/
https://ncbi.nlm.nih.gov/pubmed/28930194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9091041
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