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Identification of a novel linear B-cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

BACKGROUND: The Nucleoprotein (NP) is the most abundant and highly immunogenic protein in canine distemper virus (CDV), playing an important role in CDV viral replication and assembly. RESULTS: In this study, a specific monoclonal antibody, named C8, was produced against the NP protein C terminal (a...

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Podrobná bibliografie
Vydáno v:Virol J
Hlavní autoři: Yi, Li, Cao, Zhigang, Tong, Mingwei, Cheng, Yuening, Yang, Yong, Li, Shuang, Wang, Jianke, Lin, Peng, Sun, Yaru, Zhang, Miao, Cheng, Shipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622507/
https://ncbi.nlm.nih.gov/pubmed/28962633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0858-6
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