The Procoagulant Activity of Apoptotic Cells Is Mediated by Interaction with Factor XII

Apoptotic cells, by externalizing phosphatidylserine (PS) as a hallmark feature, are procoagulant. However, the mechanism by which apoptotic cells activate coagulation system remains unknown. Intrinsic coagulation pathway is initiated by coagulation factor XII (FXII) of contact activation system. Th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Yang, Aizhen, Chen, Fengwu, He, Chao, Zhou, Junsong, Lu, Yi, Dai, Jihong, Birge, Raymond B., Wu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622377/
https://ncbi.nlm.nih.gov/pubmed/28993777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01188
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