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COX-2 mediates PM2.5-induced apoptosis and inflammation in vascular endothelial cells

Emerging evidence demonstrated that particulate matter 2.5 (PM2.5) exposure served as an important risk factor of cardiovascular diseases. Some studies also reported that COX-2/mPGES-1/PGE2 cascade played a pathogenic role in vascular injury. However, the relationship between the PM2.5 exposure and...

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Pubblicato in:Am J Transl Res
Autori principali: Yin, Jie, Xia, Weiwei, Li, Yuanyuan, Guo, Chuchu, Zhang, Yue, Huang, Songming, Jia, Zhanjun, Zhang, Aihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622242/
https://ncbi.nlm.nih.gov/pubmed/28979673
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