Adjuvant-Mediated Epitope Specificity and Enhanced Neutralizing Activity of Antibodies Targeting Dengue Virus Envelope Protein

The heat-labile toxins (LT) produced by enterotoxigenic Escherichia coli display adjuvant effects to coadministered antigens, leading to enhanced production of serum antibodies. Despite extensive knowledge of the adjuvant properties of LT derivatives, including in vitro-generated non-toxic mutant fo...

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Vydáno v:Front Immunol
Hlavní autoři: Maeda, Denicar Lina Nascimento Fabris, Batista, Milene Tavares, Pereira, Lennon Ramos, de Jesus Cintra, Mariana, Amorim, Jaime Henrique, Mathias-Santos, Camila, Pereira, Sara Araújo, Boscardin, Silvia Beatriz, Silva, Sandriana dos Ramos, Faquim-Mauro, Eliana L., Silveira, Vanessa Barbosa, Oliveira, Danielle Bruna Leal, Johnston, Stephen Albert, Ferreira, Luís Carlos de Souza, Rodrigues, Juliana Falcão
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622152/
https://ncbi.nlm.nih.gov/pubmed/28993770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01175
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