Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains

Dopamine regulates reward, cognition, and locomotor functions. By mediating rapid reuptake of extracellular dopamine, the dopamine transporter is critical for spatiotemporal control of dopaminergic neurotransmission. Here, we use super-resolution imaging to show that the dopamine transporter is dyna...

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Udgivet i:Nat Commun
Main Authors: Rahbek-Clemmensen, Troels, Lycas, Matthew D., Erlendsson, Simon, Eriksen, Jacob, Apuschkin, Mia, Vilhardt, Frederik, Jørgensen, Trine N., Hansen, Freja H., Gether, Ulrik
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622129/
https://ncbi.nlm.nih.gov/pubmed/28963530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00790-3
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