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Selection on start codons in prokaryotes and potential compensatory nucleotide substitutions

Reconstruction of the evolution of start codons in 36 groups of closely related bacterial and archaeal genomes reveals purifying selection affecting AUG codons. The AUG starts are replaced by GUG and especially UUG significantly less frequently than expected under the neutral expectation derived fro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Belinky, Frida, Rogozin, Igor B., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622118/
https://ncbi.nlm.nih.gov/pubmed/28963504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12619-6
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