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Selection on start codons in prokaryotes and potential compensatory nucleotide substitutions

Reconstruction of the evolution of start codons in 36 groups of closely related bacterial and archaeal genomes reveals purifying selection affecting AUG codons. The AUG starts are replaced by GUG and especially UUG significantly less frequently than expected under the neutral expectation derived fro...

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Vydáno v:Sci Rep
Hlavní autoři: Belinky, Frida, Rogozin, Igor B., Koonin, Eugene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622118/
https://ncbi.nlm.nih.gov/pubmed/28963504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12619-6
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