Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction

Transcriptionally activated monocytes are recruited to the heart after acute myocardial infarction (AMI). After AMI in mice and humans, the number of extracellular vesicles (EVs) increased acutely. In humans, EV number correlated closely with the extent of myocardial injury. We hypothesized that EVs...

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Vydáno v:JCI Insight
Hlavní autoři: Akbar, Naveed, Digby, Janet E., Cahill, Thomas J., Tavare, Abhijeet N., Corbin, Alastair L., Saluja, Sushant, Dawkins, Sam, Edgar, Laurienne, Rawlings, Nadiia, Ziberna, Klemen, McNeill, Eileen, Johnson, Errin, Aljabali, Alaa A., Dragovic, Rebecca A., Rohling, Mala, Belgard, T. Grant, Udalova, Irina A., Greaves, David R., Channon, Keith M., Riley, Paul R., Anthony, Daniel C., Choudhury, Robin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621885/
https://ncbi.nlm.nih.gov/pubmed/28878126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93344
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