Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction

Transcriptionally activated monocytes are recruited to the heart after acute myocardial infarction (AMI). After AMI in mice and humans, the number of extracellular vesicles (EVs) increased acutely. In humans, EV number correlated closely with the extent of myocardial injury. We hypothesized that EVs...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Akbar, Naveed, Digby, Janet E., Cahill, Thomas J., Tavare, Abhijeet N., Corbin, Alastair L., Saluja, Sushant, Dawkins, Sam, Edgar, Laurienne, Rawlings, Nadiia, Ziberna, Klemen, McNeill, Eileen, Johnson, Errin, Aljabali, Alaa A., Dragovic, Rebecca A., Rohling, Mala, Belgard, T. Grant, Udalova, Irina A., Greaves, David R., Channon, Keith M., Riley, Paul R., Anthony, Daniel C., Choudhury, Robin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621885/
https://ncbi.nlm.nih.gov/pubmed/28878126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93344
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