Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy

Heart disease remains the leading cause of death worldwide, highlighting a pressing need to identify novel regulators of cardiomyocyte (CM) function that could be therapeutically targeted. The mammalian Hippo/Tead pathway is critical in embryonic cardiac development and perinatal CM proliferation. H...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Liu, Ruya, Lee, Jeongkyung, Kim, Byung S., Wang, Qiongling, Buxton, Samuel K., Balasubramanyam, Nikhil, Kim, Jean J., Dong, Jianrong, Zhang, Aijun, Li, Shumin, Gupte, Anisha A., Hamilton, Dale J., Martin, James F., Rodney, George G., Coarfa, Cristian, Wehrens, Xander H.T., Yechoor, Vijay K., Moulik, Mousumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621883/
https://ncbi.nlm.nih.gov/pubmed/28878117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93343
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