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Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells

Induction of necroptosis has emerged as an alternative approach to trigger programmed cell death, in particular in apoptosis-resistant cancer cells. Recent evidence suggests that kinase inhibitors targeting oncogenic B-RAF can also affect Receptor-interacting serine/threonine-protein kinase (RIP)1 a...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Feldmann, Friederike, Schenk, Barbara, Martens, Sofie, Vandenabeele, Peter, Fulda, Simone
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620249/
https://ncbi.nlm.nih.gov/pubmed/28978109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19919
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