Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures

We have developed 3D-tumoroids and tumor slice in vitro culture systems from surgical tumor specimens derived from patients with colorectal cancer (CRC) or lung cancer to evaluate immune cell populations infiltrating cultured tissues. The system incorporates patient's peripherally and tumor-der...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Finnberg, Niklas K., Gokare, Prashanth, Lev, Avital, Grivennikov, Sergei I., MacFarlane, Alexander W., Campbell, Kerry S., Winters, Ryan M., Kaputa, Karen, Farma, Jeffrey M., Abbas, Abbas El-Sayed, Grasso, Luigi, Nicolaides, Nicholas C., El-Deiry, Wafik S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5620133/
https://ncbi.nlm.nih.gov/pubmed/28977993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19965
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