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Immune checkpoint inhibitor combinations in solid tumors: opportunities and challenges

The emergence of immune ‘checkpoint inhibitors’ such as cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed death receptor 1 (PD-1) has revolutionized treatment of solid tumors including melanoma, lung cancer, among many others. The goal of checkpoint inhibitor combination therapy is to improve...

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Detalhes bibliográficos
Publicado no:Immunotherapy
Main Authors: Kyi, Chrisann, Postow, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619130/
https://ncbi.nlm.nih.gov/pubmed/27349981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt-2016-0002
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