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Influence of common and rare genetic variation on warfarin dose among African–Americans and European–Americans using the exome array

AIM: We conducted a genome-wide association study using the Illumina Exome Array to identify coding SNPs that may explain additional warfarin dose variability. PATIENTS & METHODS: Analysis was performed after adjustment for clinical variables and genetic factors known to influence warfarin dose...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Liu, Nianjun, Irvin, Marguerite R, Zhi, Degui, Patki, Amit, Beasley, T Mark, Nickerson, Deborah A, Hill, Charles E, Chen, Jinbo, Kimmel, Stephen E, Limdi, Nita A
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619051/
https://ncbi.nlm.nih.gov/pubmed/28686080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2017-0046
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