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EZH2‐mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis

EZH2, a histone H3 lysine‐27‐specific methyltransferase, is involved in diverse physiological and pathological processes including cell proliferation and differentiation. However, the role of EZH2 in liver fibrosis is largely unknown. In this study, it was identified that EZH2 promoted Wnt pathway‐s...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yang, Yang, Chen, Xiao‐xia, Li, Wan‐xia, Wu, Xiao‐qin, Huang, Cheng, Xie, Juan, Zhao, Yu‐xin, Meng, Xiao‐ming, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618695/
https://ncbi.nlm.nih.gov/pubmed/28332284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13153
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