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Genome Instability and γH2AX

γH2AX has emerged in the last 20 years as a central player in the DDR (DNA damage response), with specificity for DSBs (double-strand breaks). Upon the generation of DSBs, γ-phosphorylation extends along megabase-long domains in chromatin, both sides of the damage. The significance of this mechanism...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Georgoulis, Anastasios, Vorgias, Constantinos E., Chrousos, George P., Rogakou, Emmy P.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618628/
https://ncbi.nlm.nih.gov/pubmed/28914798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091979
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