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Hypoxia Is a Critical Parameter for Chondrogenic Differentiation of Human Umbilical Cord Blood Mesenchymal Stem Cells in Type I/III Collagen Sponges

Umbilical cord blood (UCB) is an attractive alternative to bone marrow for isolation of mesenchymal stem cells (MSCs) to treat articular cartilage defects. Here, we set out to determine the growth factors (bone morphogenetic protein 2 (BMP-2) and transforming growth factor-β (TGF-β1)) and oxygen ten...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gómez-Leduc, Tangni, Desancé, Mélanie, Hervieu, Magalie, Legendre, Florence, Ollitrault, David, de Vienne, Claire, Herlicoviez, Michel, Galéra, Philippe, Demoor, Magali
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618582/
https://ncbi.nlm.nih.gov/pubmed/28885597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091933
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