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IGF-1 Attenuates Hypoxia-Induced Atrophy but Inhibits Myoglobin Expression in C2C12 Skeletal Muscle Myotubes

Chronic hypoxia is associated with muscle wasting and decreased oxidative capacity. By contrast, training under hypoxia may enhance hypertrophy and increase oxidative capacity as well as oxygen transport to the mitochondria, by increasing myoglobin (Mb) expression. The latter may be a feasible strat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Peters, Eva L., van der Linde, Sandra M., Vogel, Ilse S. P., Haroon, Mohammad, Offringa, Carla, de Wit, Gerard M. J., Koolwijk, Pieter, van der Laarse, Willem J., Jaspers, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618538/
https://ncbi.nlm.nih.gov/pubmed/28862673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091889
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