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The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes

Lymphocytes are endowed with unique and specialized enzymatic mutagenic properties that allow them to diversify their antigen receptors, which are crucial sensors for pathogens and mediators of adaptive immunity. During lymphocyte development, the antigen receptors expressed by B and T lymphocytes a...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Bahjat, Mahnoush, Guikema, Jeroen E. J.
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618525/
https://ncbi.nlm.nih.gov/pubmed/28867784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18091876
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