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Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism

There are few available medical countermeasures against botulism and the discontinuation of the pentavalent botulinum toxoid vaccine by the Centers for Disease Control and Prevention in 2011 has resulted in the need for a safe and effective prophylactic alternative. Advances in genetic engineering h...

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Dades bibliogràfiques
Publicat a:Toxins (Basel)
Autors principals: Webb, Robert P., Smith, Theresa J., Smith, Leonard A., Wright, Patrick M., Guernieri, Rebecca L., Brown, Jennifer L., Skerry, Janet C.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5618202/
https://ncbi.nlm.nih.gov/pubmed/28869522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9090269
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