Synthesis and Immunological Evaluation of Virus-Like Particle-Milbemycin A(3)/A(4) Conjugates

Milbemycins are macrolide antibiotics with a broad spectrum of nematocidal, insecticidal, and acaricidal activity. To obtain milbemycin A(3)/A(4) derivatives suitable for chemical conjugation to protein carriers (milbemycin haptens), succinate linker and a novel 17-atom-long linker containing a term...

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Bibliografiske detaljer
Udgivet i:Antibiotics (Basel)
Main Authors: Zeltins, Andris, Turks, Māris, Skrastina, Dace, Lugiņina, Jevgeņija, Kalnciema, Ieva, Balke, Ina, Bizdēna, Ērika, Skrivelis, Vitalijs
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617982/
https://ncbi.nlm.nih.gov/pubmed/28892001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics6030018
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