A carregar...
A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst
[Image: see text] Macrolactonization of natural product analogs presents a significant challenge to both biosynthetic assembly and synthetic chemistry. In the preceding paper, we identified a thioesterase (TE) domain catalytic bottleneck processing unnatural substrates in the pikromycin (Pik) system...
Na minha lista:
| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2017
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617804/ https://ncbi.nlm.nih.gov/pubmed/28836768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b06436 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|