Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma

Primary open-angle glaucoma (POAG) is often caused by elevated intraocular pressure (IOP), which arises due to increased resistance to aqueous humor outflow (AHO). Aqueous humor flows through Schlemm’s canal (SC), a lymphatic-like vessel encircling the cornea, and via intercellular spaces of ciliary...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kim, Jaeryung, Park, Dae-Young, Bae, Hosung, Park, Do Young, Kim, Dongkyu, Lee, Choong-kun, Song, Sukhyun, Chung, Tae-Young, Lim, Dong Hui, Kubota, Yoshiaki, Hong, Young-Kwon, He, Yulong, Augustin, Hellmut G., Oliver, Guillermo, Koh, Gou Young
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617682/
https://ncbi.nlm.nih.gov/pubmed/28920924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94668
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