Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration

Choriocapillary loss is a major cause of neovascular age-related macular degeneration (NV-AMD). Although vascular endothelial growth factor (VEGF) blockade for NV-AMD has shown beneficial outcomes, unmet medical needs for patients refractory or tachyphylactic to anti-VEGF therapy exist. In addition,...

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Publicado en:Sci Adv
Autores principales: Kim, Jaeryung, Park, Jang Ryul, Choi, Jeongwoon, Park, Intae, Hwang, Yoonha, Bae, Hosung, Kim, Yongjoo, Choi, WooJhon, Yang, Jee Myung, Han, Sangyeul, Chung, Tae-Young, Kim, Pilhan, Kubota, Yoshiaki, Augustin, Hellmut G., Oh, Wang-Yuhl, Koh, Gou Young
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374104/
https://ncbi.nlm.nih.gov/pubmed/30788433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6732
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