RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism

Bile acids function not only as detergents that facilitate lipid absorption but also as signaling molecules that activate the nuclear receptor farnesoid X receptor (FXR). FXR agonists are currently being evaluated as therapeutic agents for a number of hepatic diseases due to their lipid-lowering and...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Tarling, Elizabeth J., Clifford, Bethan L., Cheng, Joan, Morand, Pauline, Cheng, Angela, Lester, Ellen, Sallam, Tamer, Turner, Martin, de Aguiar Vallim, Thomas Q.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617661/
https://ncbi.nlm.nih.gov/pubmed/28891815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94029
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