Astrocyte-elevated gene-1 confers resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase expression

Previous studies have suggested that astrocyte-elevated gene-1 (AEG-1) contributes to the mechanisms of resistance to various chemotherapeutics. In this study, we investigated whether AEG-1 expression level correlated with that of thymidylate synthase (TS), as higher TS expression is known to be ass...

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Udgivet i:Oncotarget
Main Authors: Chen, Chung-Yu, Chen, Ying-Yin, Chen, Jeremy J.W., Chen, Kuan-Yu, Ho, Chao-Chi, Shih, Jin-Yuan, Chang, Yih-Leong, Yu, Chong-Jen, Yang, Pan-Chyr
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617473/
https://ncbi.nlm.nih.gov/pubmed/28977913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18717
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