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Demethylation of the MIR145 promoter suppresses migration and invasion in breast cancer

miR-145 has been implicated in the progression of breast cancer. Here, we report that its expression is decreased in breast cancer specimens and cell lines and that this low level of expression is associated with DNA methylation of its gene, MIR145. Methylation of MIR145 has previously been correlat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Liu, Shui-Yi, Li, Xiao-Yi, Chen, Wei-Qun, Hu, Hui, Luo, Bo, Shi, Yu-Xiang, Wu, Tang-Wei, Li, Yong, Kong, Qing-Zhi, Lu, Hong-Da, Lu, Zhong-Xin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617460/
https://ncbi.nlm.nih.gov/pubmed/28977900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18686
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