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Demethylation of the MIR145 promoter suppresses migration and invasion in breast cancer

miR-145 has been implicated in the progression of breast cancer. Here, we report that its expression is decreased in breast cancer specimens and cell lines and that this low level of expression is associated with DNA methylation of its gene, MIR145. Methylation of MIR145 has previously been correlat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Shui-Yi, Li, Xiao-Yi, Chen, Wei-Qun, Hu, Hui, Luo, Bo, Shi, Yu-Xiang, Wu, Tang-Wei, Li, Yong, Kong, Qing-Zhi, Lu, Hong-Da, Lu, Zhong-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617460/
https://ncbi.nlm.nih.gov/pubmed/28977900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18686
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