Downregulation of X-linked inhibitor of apoptosis protein by ‘7-Benzylidenenaltrexone maleate’ sensitizes pancreatic cancer cells to TRAIL-induced apoptosis

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential biological anticancer agent. However, a wide range of human primary cancers, including pancreatic cancer, display resistance to apoptosis induction by TRAIL. Therefore, this resistance needs to be overcome to allow TRAIL...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, So Young, Park, Sojung, Yoo, SeonA, Rho, Jin Kyung, Jun, Eun Sung, Chang, Suhwan, Kim, Kyung Kon, Kim, Song Cheol, Kim, Inki
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617406/
https://ncbi.nlm.nih.gov/pubmed/28977846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17841
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