Proteoliposome-based full-length ZnT8 self-antigen for type 1 diabetes diagnosis on a plasmonic platform

Identified as a major biomarker for type 1 diabetes (T1D) diagnosis, zinc transporter 8 autoantibody (ZnT8A) has shown promise for staging disease risk and disease diagnosis. However, existing assays for ZnT8 autoantibody (ZnT8A) are limited to detection by soluble domains of ZnT8, owing to difficul...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wan, Hao, Merriman, Chengfeng, Atkinson, Mark A., Wasserfall, Clive H., Mcgrail, Kieran M., Liang, Yongye, Fu, Dax, Dai, Hongjie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617307/
https://ncbi.nlm.nih.gov/pubmed/28874568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711169114
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