Class II and IV HDACs function as inhibitors of osteoclast differentiation

Histone deacetylases (HDACs) are negative regulators of transcription and have been shown to regulate specific changes in gene expression. In vertebrates, eighteen HDACs have thus far been identified and subdivided into four classes (I-IV). Key roles for several HDACs in bone development and biology...

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Vydáno v:PLoS One
Hlavní autoři: Blixt, Nicholas C., Faulkner, Bora K., Astleford, Kristina, Lelich, Rosemary, Schering, Jacob, Spencer, Ekaterina, Gopalakrishnan, Rajaram, Jensen, Eric D., Mansky, Kim C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617211/
https://ncbi.nlm.nih.gov/pubmed/28953929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185441
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