Class II and IV HDACs function as inhibitors of osteoclast differentiation

Histone deacetylases (HDACs) are negative regulators of transcription and have been shown to regulate specific changes in gene expression. In vertebrates, eighteen HDACs have thus far been identified and subdivided into four classes (I-IV). Key roles for several HDACs in bone development and biology...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Blixt, Nicholas C., Faulkner, Bora K., Astleford, Kristina, Lelich, Rosemary, Schering, Jacob, Spencer, Ekaterina, Gopalakrishnan, Rajaram, Jensen, Eric D., Mansky, Kim C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617211/
https://ncbi.nlm.nih.gov/pubmed/28953929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185441
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