Class II and IV HDACs function as inhibitors of osteoclast differentiation

Histone deacetylases (HDACs) are negative regulators of transcription and have been shown to regulate specific changes in gene expression. In vertebrates, eighteen HDACs have thus far been identified and subdivided into four classes (I-IV). Key roles for several HDACs in bone development and biology...

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Bibliographic Details
Published in:PLoS One
Main Authors: Blixt, Nicholas C., Faulkner, Bora K., Astleford, Kristina, Lelich, Rosemary, Schering, Jacob, Spencer, Ekaterina, Gopalakrishnan, Rajaram, Jensen, Eric D., Mansky, Kim C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617211/
https://ncbi.nlm.nih.gov/pubmed/28953929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185441
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