Class II and IV HDACs function as inhibitors of osteoclast differentiation

Histone deacetylases (HDACs) are negative regulators of transcription and have been shown to regulate specific changes in gene expression. In vertebrates, eighteen HDACs have thus far been identified and subdivided into four classes (I-IV). Key roles for several HDACs in bone development and biology...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Blixt, Nicholas C., Faulkner, Bora K., Astleford, Kristina, Lelich, Rosemary, Schering, Jacob, Spencer, Ekaterina, Gopalakrishnan, Rajaram, Jensen, Eric D., Mansky, Kim C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617211/
https://ncbi.nlm.nih.gov/pubmed/28953929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185441
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