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A requirement for Mena, an actin regulator, in local mRNA translation in developing neurons

During neuronal development, local mRNA translation is required for axon guidance and synaptogenesis, and dysregulation of this process contributes to multiple neurodevelopmental and cognitive disorders. However, regulation of local protein synthesis in developing axons remains poorly understood. He...

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Bibliographische Detailangaben
Veröffentlicht in:Neuron
Hauptverfasser: Vidaki, Marina, Drees, Frauke, Saxena, Tanvi, Lanslots, Erwin, Taliaferro, Matthew J., Tatarakis, Antonios, Burge, Christopher B., Wang, Eric T., Gertler, Frank B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616167/
https://ncbi.nlm.nih.gov/pubmed/28735747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.06.048
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