The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior

During tumor progression, alternative splicing gives rise to different Mena protein isoforms. We analyzed how Mena11a, an isoform enriched in epithelia and epithelial-like cells, affects Mena-dependent regulation of actin dynamics and cell behavior. While other Mena isoforms promote actin polymeriza...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Balsamo, Michele, Mondal, Chandrani, Carmona, Guillaume, McClain, Leslie M., Riquelme, Daisy N., Tadros, Jenny, Ma, Duan, Vasile, Eliza, Condeelis, John S., Lauffenburger, Douglas A., Gertler, Frank B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066228/
https://ncbi.nlm.nih.gov/pubmed/27748415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35298
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